7 Best Gaming Mouse with Side Buttons

When gaming, a mouse with just two buttons and a scroll wheel doesn’t solve the purpose. You’d need a mouse that is comfortable to use in the long run and carries a right number of programmable side buttons. So, if you want the best gaming mouse with side buttons, we have lined up some great options.

You can program side buttons on mice to perform specific actions that give you an upper hand when gaming. For example, you can program one of the buttons to quickly reload your gun, so you don’t have to reach for a specific key on the keyboard. You can also use the dedicated buttons on the mouse to perform actions in other apps like browsers to go back or forward. If that sounds helpful to you, here are some of the best gaming mice with side buttons.

Before that, here are some other articles we think may interest you –

With that out of the way, let’s get started.

1. Razer DeathAdder Elite

Number of side buttons: 2

The first thing that comes to mind when you look at the Razer DeathAdder is its comfortable and ergonomic design. It comes with an accurate sensor, seven programmable buttons, and two lighting zones. It has a maximum DPI of 16,000, making it perfect for gaming. It boasts a custom 5G sensor which can easily handle accelerations up to 50g without breaking a sweat.

As aforementioned, the DeathAdder Elite sports seven buttons, including the two side buttons and two buttons present below the scroll wheel. All the buttons are unobtrusive. You can assign the function as per your preference using the Razer Synapse software.

Several users echo in their reviews on Amazon about the solid performance this mouse delivers. Apart from that, it’s comfortable to use for long periods – depending on the type of grip you have.

More importantly, the build quality is solid and is likely to last you a long time. And the high DPI and high IPS are the cherry on top for this affordable mouse.

2. Corsair Sabre RGB Gaming Mouse

Number of side buttons: 4

Another modestly-priced gaming mouse is the Corsair Sabre RGB Gaming Mouse. One of its remarkable features is its larger DPI range (for its price) of up to 10,000 DPI. The 1000hz polling rate means you get a great responsive mouse in your palms. At the same time, it’s light and comfortable and will likely fit well in most people’s hands. And the customizable lighting is a bonus.

This mouse sports a slightly wide look and it becomes apparent if you place it next to other mouse options. On the upside, all eight well-placed buttons are tactile enough to support you through the RTS (Real-time Strategy) games. Plus, you can always program them to trigger specific functions. Luckily, you won’t be hassled with accidental clicking or miss-clicks.

Unlike most mice (which have the DPI button below the scroll wheel), the DPI buttons are located at the upper-left corner of the mouse. And this unique placement makes it convenient to change the settings. After all, you have to alter the index finger slightly.

Compared to the mouse above, this one has four-zone color back-lighting, and you can tweak the colors with the aid of the iCue software. Plus, the solid build ensures the main switches and the whole mouse last a long time.

However, the Sabre has one issue. It has a soft-touch finish and you may lose grip if your palms sweat a lot during gaming.

3. Steelseries Sensei 310

Number of side buttons: 4

If you are looking for a fully ambidextrous mouse, the SteelSeries Sensei 310 makes for a good buy. It’s a fully packed mouse with a custom sensor, an excellent design, and eight programmable buttons. This mouse has two thumb buttons on either side, thanks to its ambidextrous design.

Furthermore, the textured grips on the thumb rest and the scroll wheel will help you tackle the mouse (and your gameplay) better. You can program all the buttons and lighting as you prefer.

The lighting is subtle and sits well with the mouse design. For now, the Sensei 310 has two zones and multi-color RGB lighting.

Aside from that, many users praise the custom TrueMove3 sensor for its accurate tracking, ergonomic design, and performance.

Though it has a maximum DPI of up to 12,000, the mouse comes with only two DPI settings. Plus, only one toggle lets you switch between these settings. Though the mouse looks sturdy and should do well in the long run, note that the connecting cable isn’t braided.

4. Corsair NightSword RGB

Number of side buttons: 6

With an ornamental rubberized grip, a thumb wing, and uniquely designed buttons, the Corsair Nightsword RGB is surely a looker. However, it’s not only the looks that define this gaming mouse, for it also has several features. For one, there are ten buttons, a dedicated sniper button, and is polished off with a powerful sensor. And all these combine to give you a fine gaming experience.

There are around five large buttons positioned to the left. The first set is at the top and can be easily accessed using the index finger to adjust the DPI of the mouse. The actual thumb buttons are placed immediately below them, along with a sniper button. The thumb wing makes the mouse convenient to handle.

The performance is on par with its price. It’s precise, and the response time is also excellent. But at the end of the day, the Nightsword is quite big and is only meant for you if you have bigger hands. And if you have sweaty palms, you may see yourself losing the grip far too often than you’d like.

5. Logitech G604 Lightspeed

Number of side buttons: 8

Love MMO and MOBA games? If yes, the Logitech G604 Lightspeed gaming wireless mouse with side buttons is designed just for you. The highlight of this gaming mouse is the Dual-Mode hyper-fast scroll wheel. You can push the wheel sideways in two directions. Depending on your gameplay, you can lock down the scroll wheel, or keep it unlocked if you want to scroll through maps quickly. The G604 Lightspeed has six thumb buttons.

You can define the function of these thumb buttons. You may find it difficult initially to distinguish between all of them, it gets easier with time. Aside from that, the performance is solid, thanks to the 16K Hero sensor. If we talk numbers, the maximum DPI is up to 16,000, which you can easily adjust with the top-left buttons.

It’s a wireless mouse, and you can expect the battery to last over 240 gaming hours. Yep, it’s one of the long-lasting gaming mice out there.

Overall, it’s a great mouse with reliable performance, good design and a solid grip. However, it does have a few limitations. For one, there’s no RGB lighting in this one. Secondly, it may take time to get used to the six thumb buttons. This mouse is ideal for the MMO, MOBA, or Battle Royale style game lovers.

6. Razer Naga Trinity

Number of side buttons: 12/7/2

The Razer Naga Trinity is the mouse for you if you love modular design. Yep, this one has three interchangeable plates to swap the left side of the mouse, depending on your preference. You can switch between the twelve-button, six-button, and standard two-button layout.

So, why would you buy this? The plates let you tweak the buttons depending on the games you play. And the good news is that you don’t need to change the mouse settings each time you change the plates. All of them are saved and can be loaded each time you switch the plates.

And when it comes to performance, you get the charm associated with the 2014 variant of the Razer Naga mouse. Do note that this mouse is a tad small. And if you have large hands, skip this one.

7. Logitech G502 Lightspeed

Number of side buttons: 6

The Logitech G502 Lightspeed is the one for you if you are looking for a comfortable mouse to use with your right hand. It comes with plenty of buttons. There are 11 buttons in total, including two standard thumb buttons. The highlight of this gaming mouse is its sharp and modern look with a generous thumb rest.

The G502 Lightspeed boasts a maximum DPI of 16,000 and is a great performer. Gamers and reviews have praised its performance. The folks at Toms Guide put the performance in this way, “the G502 Lightspeed performed flawlessly in games.”

Aside from that, the G502 Lightspeed comes with a customizable weight system. You can add up to 16 grams of additional weights (2×4 grams + 4×2 grams), as per your preference. And typical of most gaming mice, you can customize the colors of the DPI indicators and the Logitech G logo.

FAQs for Gaming Mouse With Side Buttons

1. Are all gaming mice with side buttons programmable?

Yes, you can program the side buttons on all mice. However, only a few mouse models are compatible with brand’s official software. So, you might have to use in-game settings to program the buttons in specific games.

2. Is a gaming mouse with side buttons ergonomic?

Not all mice are ergonomic. If you want a mouse that won’t harm your wrist, we suggest an ergonomic gaming mouse.

3. Can I use a mouse with side buttons on a Mac?

Yes, you can use mice with side buttons with a Mac. However, you may not have access to programming software on Mac with mice from all brands. So, ensure the mouse manufacturer has an app to customize the buttons on macOS.

Hello, Precision!

So, which PC games do you like to play the most? Is it PUBG (check PUBG wallpapers) or other games like Metro Exodus and Call of Duty? Regardless of which game you spend the most hours on, a good gaming mouse with side buttons can improve your gaming experience.

Last updated on 04 May, 2023

The above article may contain affiliate links which help support Guiding Tech. However, it does not affect our editorial integrity. The content remains unbiased and authentic.